Iron-sulphur clusters in electron transfer, catalysis and control.
نویسندگان
چکیده
594 Iron-sulphur clusters in electron transfer, catalysis and control Andrew J. Thomson, Jacques Breton, Simon J. George, Julea N. Butt,* Fraser A. Armstrong* and E. Claude Hatchikiant School of Chemical Sciences, University of East Anglia, Norwich NR4 7TJ, U.K., *Department of Chemistry, University of California at Irvine, Irvine, CA 927 17, U.S.A., and tCNRS-LCB., 3 I , Chemin Joseph, Aiguier-PB 781, I3277 Marseille Cedex 9, France
منابع مشابه
Biosynthesis of iron-sulphur clusters is a complex and highly conserved process.
Iron-sulphur ([Fe-S]) clusters are simple inorganic prosthetic groups that are contained in a variety of proteins having functions related to electron transfer, gene regulation, environmental sensing and substrate activation. In spite of their simple structures, biological [Fe-S] clusters are not formed spontaneously. Rather, a consortium of highly conserved proteins is required for both the fo...
متن کاملElectron-spin-resonance/electron-paramagnetic-resonance spectroscopy of iron-sulphur enzymes.
The conjugated iron-sulphur proteins are enzymes that contain iron-sulphur clusters, which are paramagnetic in certain oxidation states. Numerous enzymes of this type have been isolated (Palmer, 1975; Cammack, 1979; Yoch & Carithers, 1979), and whole books have been devoted to them (Lovenberg, 1977; Spiro, 1982). Most of them (aconitase being an exception) are oxidoreductases. By using e.p.r. (...
متن کاملMobilization of the iron centre in IscA for the iron-sulphur cluster assembly in IscU.
The biogenesis of iron-sulphur clusters requires the co-ordinated delivery of both iron and sulphur. It is now clear that sulphur in iron-sulphur clusters is derived from L-cysteine by cysteine desulphurases. However, the iron donor for the iron-sulphur cluster assembly still remains elusive. Our previous studies indicated that Escherichia coli IscA, a member of the iron-sulphur cluster assembl...
متن کاملReactions of complex metalloproteins studied by protein-film voltammetry
The following review explores applications of voltammetric methods for observing reactions of complex metalloproteins. Attention is focused upon the technique of ‘protein-film voltammetry’, in which the protein molecules under investigation are adsorbed on the electrode surface and electrochemically ‘interrogated.’ The experiments address a minuscule sample with high sensitivity, and optimal co...
متن کاملBiogenesis of iron-sulfur cluster proteins in plastids.
Iron-sulfur (Fe-S) clusters are co-factors of proteins that perform a number of biological roles, including electron transfer, redox and non-redox catalysis, regulation of gene expression, and as sensors within all living organisms, prokaryotes and eukaryotes. These clusters are thought to be among the oldest structures found in biological cells. In chloroplasts, Fe-S clusters play a key role i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Biochemical Society transactions
دوره 19 3 شماره
صفحات -
تاریخ انتشار 1991